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MailRun
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Blog > Tools> MailRun
Vlad Mae | Published: | min read | reads
Scaling cold email is hard. You buy domains, set up inboxes, and wait two weeks to warm them up. Then a spam filter flags your IP, and you have to start over. It wastes time and kills your reply rates. You need a reliable infrastructure that scales without burning your budget. Most providers sell basic accounts and leave the heavy lifting to you. Finding a setup that actually keeps you in the primary inbox is the real challenge.

This article compares two cold email infrastructure providers – Maildoso.ai and MailRun – to help you decide which one fits your outreach operation.
Key Takeaways
  • MailRun builds automated email infrastructure exclusively on Microsoft Azure.
  • They isolate your domains to protect your sender reputation.
  • Maildoso.ai gives you more flexibility to use Google, Microsoft, or SMTP.
  • Maildoso.ai costs significantly less to start and scale.

MailRun Review

MailRun main page screenshot
MailRun builds premium email infrastructure using Microsoft Azure. They target enterprise senders who want high security and speed. They automate the entire process, from buying the domains to creating the inboxes. They put your accounts on isolated tenants. This means you do not share a server environment with other senders, which protects your reputation. They charge a premium for this security.

Rating & Reviews

MailRun does not have a public profile on G2 or Trustpilot.

"mailrun.ai (you can use the code JoinStuartAtMailRun for a little discount) or slicey.ai is who I would use." — Anyone have a good source for bulk Microsoft accounts?

MailRun Pros

🟢 Azure infrastructure: Microsoft Azure IPs generally have high trust and bypass strict corporate spam filters easily.
🟢 Isolated setup: They isolate your domains so other spammers cannot ruin your reputation.
🟢 Full automation: They handle everything via API, pushing the accounts directly to your sending tool.

MailRun Cons

🔴 Very expensive: Their cheapest plan is $129 a month, making it hard for smaller teams to start.
🔴 Microsoft only: You cannot diversify your sending with Google Workspace accounts.
🔴 Strict limits: They only allow 10 inboxes per domain, forcing you to buy more domains to scale.

Maildoso Review

Maildoso dashboard
Maildoso dashboard (mobile)
Maildoso isn’t a complex management suite or a sequence builder – we know that real outreach needs a rock-solid foundation. We understand how the inbox works way better than those "all-in-one" platforms like Inboxkit. From our self-healing mailbox rotation to automated email deliverability infrastructure checks, we do all the technical "dirty work" for you, so you can stop worrying about the tech and get back to closing deals.

We provide high-authority mailboxes designed to stay healthy for months, not weeks, allowing your outreach team to focus on the 1% of deals that matter rather than the 99% of tech that usually breaks. It’s a specialized environment for agencies looking for a reliable SMTP mailbox for agencies that have graduated from generalist tools.

Rating & Reviews

G2: 4.7/5 (181 reviews)

"For the price point it's been worth it for us. We're sending around 1,500-2,000 emails/day across those 100 mailboxes and reply rates have been decent (2.8-3.2% depending on the campaign, but that's more about copy and targeting obviously). The infrastructure has been stable enough that i'm not constantly putting out fires anymore which was the whole point." (Reddit)

"Checking back in after another 14 days of volume. We’re officially at 500 mailboxes now and the infrastructure is holding up remarkably well. Only 14 boxes are currently in the "cooling off" period, which is less than 3% of the fleet (totally manageable). Reply rates are hovering at 2.3%, keeping our cost per reply at that $0.10 mark. Honestly, the biggest win so far isn't just the price, it’s the lack of "clustering" issues that usually plague us at this volume on GW. (Reddit)"

Maildoso Pros

🟢 Dynamic IP Rotation: We don't just "aim" for the inbox – we engineer it. Our system automatically rotates your IP addresses in real-time. If an IP gets flagged or blacklisted, we instantly swap it for a clean one before your campaign takes a hit, ensuring your emails consistently land in the primary inbox rather than getting stuck in spam.
🟢 Self-Healing Rotation System: An automated resting period for mailboxes every two weeks that clears provider flags and recovers reputation on autopilot.
🟢 Hybrid Flexibility: The ability to seamlessly blend high-authority Google Workspace accounts with high-volume SMTP mailboxes.
🟢 Global Customer Domain Tracking: Proprietary technology that allows you to safely include links without compromising your sender reputation.
🟢 Automated Inbox Placement Tests: Free email deliverability infrastructure testing every three days for all mailboxes, giving you real-time visibility into your health.
🟢 Unlimited Technical Audits: Free live sessions with experts who resolve up to 80% of issues through deep server-level forensic audits.
🟢 Advanced Captcha Protection: Technical barriers that shield your outreach domains from being linked back to your primary corporate assets.

Maildoso Cons

🔴 Conservative Limits: We suggest sticking to 15 emails a day per box to keep your domains healthy for the long run. You are free to send more if you choose, but be aware that aggressive "blasting" is a fast track to burning your reputation.
🔴 Google/SMTP Focus: We do not support native Microsoft 365/Outlook environments at this time.
We analyzed 10,000 outbound campaigns to create the ultimate guide on the most common mistakes – it solves up to 80% of all deliverability problems (according to our clients).
Facing deliverability issues?
GUIDES

Detailed Pricing Comparison

Mailbox type
Price per mailbox
Minimum package
Maildoso SMTP (domains included)
$1.8-2.5
$28
Maildoso GW
$2.7-4
$40
MailRun
$0.9-1.3
$129

Feature Comparison Table

Feature
Maildoso
MailRun
Mailbox types
SMTP, GW
Azure
API Availability
Full access (on all plans)
No access
IP type
IP rotation (best for deliverability)
Shared IPs
Self-healing mailboxes
Support
Email, Chat, Slack, Tech Audits
Chat, Email
Done-For-You
Refund policy
30-day guarantee
Strictly no refunds
Trials
300 mailboxes for 30 days
Final rating
⭐⭐⭐⭐⭐
⭐⭐

Why Infrastructure Matters

When you evaluate cold email providers, you have to look at the underlying technology. A few years ago, you could buy basic Google Workspace accounts, warm them up, and send thousands of emails. You cannot do that anymore. Google and Microsoft use AI to track sending patterns. If your infrastructure relies on static IPs or leaves an obvious footprint, the spam filters will catch you.

This is where Maildoso.ai changes the game. We use intelligent IP rotation. The system constantly shifts the IP address you send from. Spam filters cannot easily tie your domain to a single, burned IP address.

We also use self-healing mailboxes. In a normal setup, if Google flags one of your inboxes, your campaign stops. You have to log in, figure out what went wrong, and fix it manually. Maildoso.ai automates this. The system detects the problem, pauses the bad inbox, runs a recovery protocol, and routes your emails through healthy inboxes. Your campaigns keep running, and you do not lose a day of sending.

The True Cost of Bad Deliverability

Do not choose a provider just because they offer the cheapest inboxes. Cheap infrastructure always costs more in the long run. When your deliverability drops, you pay for it in three ways:

  1. You burn expensive leads. Good B2B data costs money. If your emails land in the spam folder, you waste those leads. You pay for contacts who never even see your pitch.
  2. You destroy your domains. Once spam filters flag a domain, it is incredibly hard to fix. You usually have to throw the domain away, buy a new one, and start the warm-up process all over again.
  3. You lose revenue. Every email that goes to spam is a missed meeting. In B2B sales, missing one connection can cost you thousands of dollars in closed revenue.
You have to treat cold email infrastructure as an investment. Maildoso.ai gives you the technical tools to protect your domains and keep your emails in the primary inbox. It is the only way to scale outbound sales profitably.

Final Thoughts

MailRun offers mailboxes built on Azure infrastructure. While these mailboxes are very cheap (averaging around $1), the savings are illusory rather than real:

Volume Limitations: On average, you can only send 3–5 emails per mailbox (as opposed to 30 emails on Google Workspace accounts). This means you’ll need 6 times as many mailboxes, making the real price 6 times higher.

Reliability Issues: We receive reports almost weekly that yet another Azure-based provider has been blocked. From a reliability standpoint, they are much worse – even worse than SMTP (and incidentally, SMTP often delivers better results than Google Workspace).

FAQ

  • Q:
    How do MailRun and Maildoso.ai differ?
    A:
    MailRun only uses Microsoft Azure and focuses on isolating your domains. Maildoso.ai lets you use multiple providers and focuses on IP rotation and self-healing mailboxes.
  • Q:
    Are Microsoft Azure accounts better than Google Workspace?
    A:
    No, no, no. Azure mailboxes are extremely unreliable and fall short of every other type of mailbox.
  • Q:
    Which is better for an agency?
    A:
    Maildoso.ai. The API access and automated recovery tools make it much easier to manage multiple clients at scale.
  • Q:
    Do both offer API access?
    A:
    Maildoso provides full API access. For MailRun, it's not specified.
Most cold emails fail simply because they land in spam. People never even see your offer.
Our SMTP and Google Workspace mailboxes are built specifically for outbound; this means your emails will finally be seen, and you’ll start getting more positive replies.
Boost your outbound with our infrastructure!

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